SCHEMBL20796901

SCHEMBL20796901

C=CC(=O)OCCC#N.C=CC(=O)OCCOC

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.50
ALDH1A1 P00352 5/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.46
CYP3A4 P08684 2/20 0.46
THRB P10828 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.34
MAPK1 P28482 1/20 0.34
ADORA2A P29274 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33946 0.89
Acetonitrile SCHEMBL11781454 0.87 TSHR (0.55) TSHRALDH1A1TP53HIF1AHSD17B10
Lithium SCHEMBL30027291 0.87 TSHR (0.54) TSHRALDH1A1TP53HIF1AHSD17B10
Butadiene SCHEMBL10894736 0.85 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL38483 0.85
SCHEMBL9472105 0.84 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid SCHEMBL21799261 0.84 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL20796900 0.84 TSHR (0.38) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL23130998 0.83 TSHR (0.64) TSHRALDH1A1TP53HIF1AHSD17B10
Ethylene SCHEMBL15417912 0.83 TSHR (0.64) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679080-A1 MULTI COMPONENT DISPERSANT BYK-Chemie GmbH (DE) 2020-07-15 EP disclosed
WO-2019048365-A1 MULTI COMPONENT DISPERSANT BYK-CHEMIE GMBH (DE) 2019-03-14 WO disclosed