Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.67 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24806223 | 0.84 | GABRR1 (0.77) | GABRR1ENPEPCYP1A2BLMACE2 | |
| SCHEMBL11491423 | 0.81 | GABRR1 (0.52) | GABRR1ENPEPCYP1A2NAALAD2FOLH1 | |
| SCHEMBL2868545 | 0.81 | GABRR1 (0.52) | GABRR1ENPEPCYP1A2NAALAD2FOLH1 | |
| SCHEMBL11924540 | 0.80 | — | — | |
| SCHEMBL164117 | 0.80 | — | — | |
| SCHEMBL14518787 | 0.80 | — | — | |
| SCHEMBL2420111 | 0.80 | SLC7A5 (0.58) | GABRR1SLC7A5GSR | |
| SCHEMBL199134 | 0.80 | SLC7A5 (0.58) | GABRR1SLC7A5GSR | |
| SCHEMBL8015716 | 0.80 | SLC7A5 (0.58) | GABRR1SLC7A5GSR | |
| SCHEMBL6138683 | 0.80 | SLC7A5 (0.58) | GABRR1SLC7A5GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046981-B2 | Host cell modified to produce lactams | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-29 | — | — | US | disclosed |
| US-10227622-B2 | Host cell modified to produce 2-pyrrolidone | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-12 | — | — | US | disclosed |