Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.44 |
| ▸ | LATS1 | O95835 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17615552 | 0.89 | LATS1 (0.47) | CSNK2A1CSNK2A2CSNK2BLATS1KDM4C | |
| SCHEMBL17503825 | 0.88 | KDM4C (0.51) | CSNK2A1CSNK2A2CSNK2BKDM4C | |
| SCHEMBL17615556 | 0.88 | LATS1 (0.49) | CSNK2A1CSNK2A2CSNK2BLATS1KDM4C | |
| SCHEMBL20239677 | 0.86 | LATS1 (0.47) | CSNK2A1CSNK2A2CSNK2BLATS1KDM4C | |
| SCHEMBL17891438 | 0.86 | KDM4C (0.44) | LATS1KDM4CFGFR2 | |
| SCHEMBL17623576 | 0.85 | LATS1 (0.39) | CSNK2A1CSNK2A2CSNK2BLATS1KDM4C | |
| SCHEMBL17602130 | 0.83 | LATS1 (0.47) | CSNK2A1CSNK2A2CSNK2BLATS1KDM4C | |
| SCHEMBL17602231 | 0.81 | KDM4C (0.59) | KDM4C | |
| SCHEMBL17503810 | 0.81 | SMN1; SMN2 (0.54) | HTT | |
| SCHEMBL17615722 | 0.81 | KDM4C (0.47) | KDM4CUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453710-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2019-03-13 | — | — | EP | disclosed |