Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GIPR | P48546 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20808133 | 1.00 | TP53 (0.45) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20808102 | 1.00 | TP53 (0.45) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20808078 | 1.00 | TP53 (0.45) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16606889 | 0.93 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AGCGR | |
| SCHEMBL17955905 | 0.93 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AGCGR | |
| SCHEMBL17969711 | 0.93 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AGCGR | |
| SCHEMBL16606947 | 0.93 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AGCGR | |
| SCHEMBL16606854 | 0.93 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AGCGR | |
| SCHEMBL16606864 | 0.93 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AGCGR | |
| SCHEMBL20808134 | 0.91 | TP53 (0.43) | TP53NPC1RAB9AGCGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050875-B1 | NOVEL IMIDAZOLE DERIVATIVE AND THERAPEUTICAL USE THEREOF | UNIV YONSEI IACF (KR) | 2019-03-13 | — | — | EP | disclosed |