Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 19/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345540 | 0.80 | FGFR2 (0.65) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345738 | 0.78 | FGFR2 (0.47) | FGFR2FGFR1FGFR4FGFR3KDR | |
| SCHEMBL15345471 | 0.77 | FGFR2 (0.63) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345469 | 0.77 | FGFR2 (0.63) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL16236968 | 0.76 | ABL1 (0.43) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL29223867 | 0.76 | FGFR2 (0.46) | FGFR2FGFR1FGFR4FGFR3KDR | |
| SCHEMBL16254859 | 0.76 | ABL1 (0.58) | FGFR2FGFR1FGFR4FGFR3KDR | |
| SCHEMBL30900846 | 0.76 | FGFR2 (0.46) | FGFR2FGFR1FGFR4FGFR3KDR | |
| SCHEMBL27980322 | 0.75 | FGFR2 (0.57) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345526 | 0.74 | LRRK2 (0.46) | FGFR2FGFR1FGFR4FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986257-A | Novel heterocyclic compound | 首药控股(北京)股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| EP-3023100-B1 | ANTITUMOR DRUG FOR INTERMITTENT ADMINISTRATION OF FGFR INHIBITOR | TAIHO PHARMACEUTICAL CO LTD (JP) | 2019-03-13 | — | — | EP | disclosed |