Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20810441 | 0.88 | MAPK1 (0.47) | MAPK1MEN1KMT2AGAAKDM4E | |
| SCHEMBL20810569 | 0.86 | MAPK1 (0.46) | MAPK1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL20810494 | 0.86 | SMN1; SMN2 (0.52) | MAPK1SMN1; SMN2MAPTGAAACACB | |
| SCHEMBL16800036 | 0.85 | MAPK1 (0.45) | MAPK1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL20810565 | 0.85 | MAPK1 (0.43) | MAPK1MEN1KMT2AGAAKDM4E | |
| SCHEMBL18020997 | 0.85 | MAPK1 (0.44) | MAPK1MEN1KMT2AGAAKDM4E | |
| SCHEMBL20810537 | 0.85 | MAPK1 (0.44) | MAPK1MEN1KMT2AGAAKDM4E | |
| SCHEMBL20810370 | 0.84 | MAPK1 (0.43) | MAPK1MEN1KMT2AMAPTGAA | |
| SCHEMBL18020996 | 0.84 | MAPK1 (0.43) | MAPK1MEN1KMT2AGAAKDM4E | |
| SCHEMBL20810307 | 0.83 | SMN1; SMN2 (0.48) | MAPK1MEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077369-B1 | BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS AND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS | UCL BUSINESS PLC (GB) | 2019-03-13 | — | — | EP | disclosed |