Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965608 | 0.80 | TSHR (0.42) | KMT2ATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL22537921 | 0.76 | CA12 (0.56) | KMT2ATSHRSMN1; SMN2CA9CA12 | |
| SCHEMBL14601507 | 0.74 | TSHR (0.43) | KMT2ATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL13841443 | 0.73 | TSHR (0.42) | KMT2ATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL17267013 | 0.72 | TSHR (0.39) | KMT2ATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL14601506 | 0.71 | TSHR (0.56) | NPSR1KMT2ATSHRCHRM2CHRM4 | |
| SCHEMBL22965609 | 0.70 | TSHR (0.40) | KMT2ATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL30577671 | 0.69 | TSHR (0.42) | KMT2ATSHRCHRM2CHRM4CHRM1 | |
| SCHEMBL19559915 | 0.68 | SMN1; SMN2 (0.35) | NPSR1KMT2ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL10795414 | 0.68 | KMT2A (0.39) | NPSR1KMT2ATSHRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019051257-A2 | METHODS FOR TREATING HEPATITIS B INFECTIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-03-14 | — | — | WO | disclosed |