Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.74 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.49 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.49 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.49 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20815812 | 1.00 | CAPN1 (0.74) | CAPN1CTSLPSMB5CTSKCTSB | |
| SCHEMBL20815816 | 0.95 | CAPN1 (0.68) | CAPN1CTSLPSMB5CTSKCTSB | |
| SCHEMBL20815814 | 0.95 | CAPN1 (0.68) | CAPN1CTSLPSMB5CTSKCTSB | |
| SCHEMBL21526183 | 0.92 | CAPN1 (0.71) | CAPN1CTSLPSMB5CTSKCTSS | |
| SCHEMBL21526184 | 0.92 | CAPN1 (0.71) | CAPN1CTSLPSMB5CTSKCTSS | |
| SCHEMBL365076 | 0.90 | CAPN1 (0.75) | CAPN1CTSLPSMB5CTSB | |
| SCHEMBL19552326 | 0.90 | CAPN1 (0.75) | CAPN1CTSLPSMB5CTSB | |
| SCHEMBL20815833 | 0.90 | CAPN1 (0.67) | CAPN1CTSLPSMB5PSMB11PSMA7 | |
| SCHEMBL20815830 | 0.90 | CAPN1 (0.67) | CAPN1CTSLPSMB5PSMB11PSMA7 | |
| SCHEMBL21554807 | 0.89 | CAPN1 (0.68) | CAPN1CTSLPSMB5CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191112-B1 | DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION | LANDSTEINER GENMED S L (ES) | 2019-03-20 | — | — | EP | disclosed |