SCHEMBL2082265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2082627	0.85	BRAF (0.78)	BRAFMAPK14PTK2ABL1
	SCHEMBL2083910	0.82	MAPK14 (0.56)	BRAFMAPK14PTK2ABL1AXL
	SCHEMBL5054904	0.80	MAPK14 (0.61)	BRAFMAPK14ABL1AXLSRC
	SCHEMBL5062447	0.79	MAPK13 (0.59)	BRAFMAPK14PTK2ABL1AXL
	SCHEMBL2082740	0.79	MAPK14 (0.78)	MAPK14PTK2MAPK13MAPK12MAPK11
	SCHEMBL5062003	0.78	ABL1 (0.76)	BRAFMAPK14PTK2ABL1AXL
	SCHEMBL5062000	0.78	MAP3K7 (0.61)	BRAFMAPK14ABL1AXLSRC
	SCHEMBL2083312	0.78	FLT3 (0.52)	BRAFMAPK14ABL1AXLSRC
	SCHEMBL2926831	0.78	MAPK14 (0.49)	BRAFMAPK14PTK2ABL1AXL
	SCHEMBL2080660	0.77	MAPK14 (0.64)	BRAFMAPK14PTK2ABL1AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.