Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20826107 | 0.80 | HPGD (0.62) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL20826159 | 0.79 | HPGD (0.57) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL10720984 | 0.79 | HPGD (0.76) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL21241853 | 0.78 | HPGD (0.61) | HPGDL3MBTL3ALDH1A1MEN1KMT2A | |
| SCHEMBL30288407 | 0.78 | HPGD (0.61) | HPGDL3MBTL3ALDH1A1MEN1KMT2A | |
| SCHEMBL7127339 | 0.77 | HPGD (0.77) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9613683 | 0.77 | KDM1A (0.44) | L3MBTL3L3MBTL1ALDH1A1L3MBTL4KDM1A | |
| SCHEMBL2743918 | 0.75 | HPGD (0.53) | HPGDL3MBTL3L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2568668 | 0.75 | HPGD (0.58) | HPGDL3MBTL3ALDH1A1MEN1KMT2A | |
| SCHEMBL6484438 | 0.74 | HPGD (0.56) | HPGDSMN1; SMN2POLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055590-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. (US) | 2019-03-21 | — | — | WO | disclosed |