Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883731 | 0.83 | MAPK1 (0.62) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL8324962 | 0.81 | MAPK1 (0.61) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL2251401 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL3313790 | 0.80 | KMT2A (0.45) | PARP1KDM4EL3MBTL1P4HTMPKM | |
| SCHEMBL30346498 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL1437036 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL16417282 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL2329789 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL127824 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM | |
| SCHEMBL2631699 | 0.80 | MAPK1 (0.59) | MAPK1PARP1KDM4EL3MBTL1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |