Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22920292 | 0.96 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL1791354 | 0.96 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL3281620 | 0.96 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL18804731 | 0.96 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2740837 | 0.96 | MEN1 (0.61) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL15450134 | 0.94 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL13538737 | 0.94 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL14783340 | 0.94 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL12970242 | 0.94 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL2740831 | 0.94 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055401-A1 | POLYURETHANE INSULATION FOAM COMPOSITION COMPRISING HALOGENATED OLEFINS | HUNTSMAN INTERNATIONAL LLC (US) | 2019-03-21 | — | — | WO | disclosed |