Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.52 |
| ▸ | TRPC5 | Q9UL62 | 8/20 | 0.46 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20832026 | 0.81 | TIPARP (0.62) | POLBALDH1A1TIPARPTRPC5 | |
| SCHEMBL23573187 | 0.78 | POLB (0.63) | POLBALDH1A1TIPARPTRPC5TRPC4 | |
| SCHEMBL20831259 | 0.77 | POLB (0.49) | POLBALDH1A1TIPARPTRPC5TRPC4 | |
| SCHEMBL20818330 | 0.77 | POLB (0.76) | POLBALDH1A1TIPARPTRPC5 | |
| SCHEMBL20831865 | 0.77 | POLB (0.55) | POLBALDH1A1TIPARPTRPC5TRPC4 | |
| SCHEMBL20832093 | 0.75 | POLB (0.51) | POLBALDH1A1TIPARPTRPC5TRPC4 | |
| SCHEMBL14081025 | 0.71 | POLB (0.76) | POLBALDH1A1TIPARPTRPC5 | |
| SCHEMBL20818504 | 0.71 | TIPARP (0.52) | POLBALDH1A1TIPARPTRPC5TRPC4 | |
| SCHEMBL24177012 | 0.70 | POLB (0.60) | POLBALDH1A1TIPARPTRPC5 | |
| SCHEMBL20818123 | 0.70 | POLB (0.51) | POLBALDH1A1TIPARPTRPC5TRPC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |