SCHEMBL208329

SCHEMBL208329

NC(=O)C(C(=O)O)N1CCCC1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 1/20 0.44
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.37
FDPS P14324 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8417412 0.98 DPP7 (0.47) DPP7LMNAGAAFDPSL3MBTL1
SCHEMBL10509650 0.85 DPP7 (0.42) DPP7LMNAGAAFDPSL3MBTL1
SCHEMBL11173567 0.85 DPP7 (0.45) DPP7LMNAGAAFDPS
SCHEMBL3969170 0.82 DPP7 (0.48) DPP7LMNAGAAFDPS
Ammonia Solution, Strong SCHEMBL10713045 0.80 DPP7 (0.47) DPP7LMNAGAAFDPS
SCHEMBL5824292 0.79 DPP7 (0.34) DPP7LMNAFDPSL3MBTL1
SCHEMBL2353452 0.79 CPN1 (0.31)
SCHEMBL10724095 0.74 DPP7 (0.43) DPP7LMNAGAA
SCHEMBL10730362 0.74 DPP7 (0.43) DPP7LMNAGAA
SCHEMBL6243407 0.70 DPP7 (0.42) DPP7LMNAGAAFDPSL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088776-B2 Biphenyl amide lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 ELI LILLY AND COMPANY (US) 2012-01-03 US disclosed
EP-2307401-A2 ANTINEOPLASTIC DERIVATIVES OF 4-OXO-1,4-DIHYDRO-QUINOLINE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF Sanofi-Aventis (FR) 2011-04-13 EP disclosed