Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833048 | 1.00 | SLC6A4 (0.40) | SLC6A4SLC6A3KDM4ENPC1CYP1A2 | |
| Hydrochloric Acid SCHEMBL31706813 | 0.98 | SLC6A4 (0.39) | SLC6A4SLC6A3KDM4ENPC1CYP1A2 | |
| SCHEMBL22260515 | 0.79 | SLC6A4 (0.30) | SLC6A4SLC6A3 | |
| SCHEMBL26732229 | 0.79 | SLC6A4 (0.40) | SLC6A4SLC6A3KDM4ENPC1CYP1A2 | |
| SCHEMBL20833211 | 0.72 | KDM1A (0.41) | SLC6A4SLC6A3MAPK1KDM1A | |
| SCHEMBL20833501 | 0.72 | KDM1A (0.41) | SLC6A4SLC6A3MAPK1KDM1A | |
| SCHEMBL20833495 | 0.72 | KDM1A (0.41) | SLC6A4SLC6A3MAPK1KDM1A | |
| SCHEMBL4475988 | 0.72 | — | — | |
| SCHEMBL4475990 | 0.72 | — | — | |
| SCHEMBL20833151 | 0.71 | SLC6A4 (0.40) | SLC6A4SLC6A3KDM4ENPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191252-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-09-24 | — | — | WO | disclosed |
| WO-2019055951-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2019-03-21 | — | — | WO | disclosed |