Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.75 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458032 | 1.00 | CAPN1 (0.75) | CAPN1CAPN2CTSKCTSLCTSB | |
| SCHEMBL4402033 | 1.00 | CAPN1 (0.75) | CAPN1CAPN2CTSKCTSLCTSB | |
| SCHEMBL21458034 | 0.92 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL4395935 | 0.92 | CAPN1 (0.72) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL20873422 | 0.92 | CAPN1 (0.75) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL4393092 | 0.92 | CAPN1 (0.75) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL8293258 | 0.91 | CAPN1 (0.63) | CAPN1 | |
| SCHEMBL21457982 | 0.91 | CAPN1 (0.62) | CAPN1CAPN2CTSKCTSLCTSB | |
| SCHEMBL4390231 | 0.91 | CAPN1 (0.62) | CAPN1CAPN2CTSKCTSLCTSB | |
| SCHEMBL20880271 | 0.91 | CAPN1 (0.70) | CAPN1CAPN2CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190270770-A1 | DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION | LANDSTEINER GENMED S L | 2019-09-05 | — | — | US | disclosed |
| US-10294269-B2 | Dipeptidyl ketoamide compounds and their use for the treatment and/or prevention of fat accumulation | LANDSTEINER GENMED, S.L. (ES) | 2019-05-21 | — | — | US | disclosed |
| EP-3191112-B1 | DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION | LANDSTEINER GENMED S L (ES) | 2019-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294269-B2 | Dipeptidyl ketoamide compounds and their use for the treatment and/or prevention of fat accumulation | DPP4, DPP3, DPP8 | CAPN1 1457/4885CAPN2 1847/4885CTSK 605/4885 |
| US-20190270770-A1 | DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION | DPP4, DPP3, DPP8 | CAPN1 1457/4885CAPN2 1847/4885CTSK 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.