⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21205631 | 0.78 | — | — | |
| SCHEMBL20177957 | 0.74 | — | — | |
| SCHEMBL21205701 | 0.64 | — | — | |
| SCHEMBL8048231 | 0.64 | — | — | |
| SCHEMBL12786645 | 0.64 | — | — | |
| SCHEMBL22810527 | 0.63 | — | — | |
| SCHEMBL21450784 | 0.63 | — | — | |
| SCHEMBL21205529 | 0.63 | — | — | |
| SCHEMBL21414657 | 0.60 | — | — | |
| SCHEMBL4536846 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055750-A1 | PYRAZOLOPYRIMIDINONE COMPOUNDS AND USES THEREOF | Aduro Biotech, Inc. (US) | 2019-03-21 | — | — | WO | disclosed |