Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL29096603 | 0.96 | HSD17B10 (0.62) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| SCHEMBL29404347 | 0.91 | HSD17B10 (0.78) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| SCHEMBL7624693 | 0.91 | HSD17B10 (0.78) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| Benzene SCHEMBL28110156 | 0.91 | HSD17B10 (0.78) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| SCHEMBL68291 | 0.91 | HSD17B10 (0.78) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| Lithium SCHEMBL7732118 | 0.89 | HSD17B10 (0.75) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| SCHEMBL7732114 | 0.89 | HSD17B10 (0.75) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL3689123 | 0.89 | HSD17B10 (0.75) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| SCHEMBL28609543 | 0.89 | HSD17B10 (0.75) | HSD17B10PTPN1MEN1KMT2ATSHR | |
| Charcoal, Activated SCHEMBL5746941 | 0.89 | HSD17B10 (0.75) | HSD17B10PTPN1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190091970-A1 | LAMINATE AND FRONT PANEL OF IMAGE DISPLAY APPARATUS, IMAGE DISPLAY APPARATUS, MIRROR WITH IMAGE DISPLAY FUNCTION, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL HAVING LAMINATE | FUJIFILM CORPORATION (JP) | 2019-03-28 | — | — | US | disclosed |