Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 14/20 | 0.79 |
| ▸ | PPARD | Q03181 | 9/20 | 0.72 |
| ▸ | PPARG | P37231 | 9/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20852075 | 0.93 | NR1H4 (0.68) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839595 | 0.89 | NR1H4 (0.66) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839500 | 0.88 | NR1H4 (1.00) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20852288 | 0.88 | NR1H4 (0.61) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20852070 | 0.88 | NR1H4 (0.75) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839624 | 0.85 | NR1H4 (0.78) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839783 | 0.85 | NR1H4 (0.80) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839737 | 0.84 | NR1H4 (0.80) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839977 | 0.84 | NR1H4 (0.77) | NR1H4PPARDPPARGPPARAHSPH1 | |
| SCHEMBL20839687 | 0.84 | NR1H4 (1.00) | NR1H4PPARDPPARGPPARAHSPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |