Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.41 |
| ▸ | GEMIN4 | P57678 | 1/20 | 0.38 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.36 |
| ▸ | PLK4 | O00444 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787736 | 0.90 | F13A1 (0.47) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL20840808 | 0.84 | HSP90AB1 (0.56) | MKNK2HSP90AB1MAPTRAB9ANPSR1 | |
| SCHEMBL19418195 | 0.83 | MKNK2 (0.63) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL4510614 | 0.83 | MKNK2 (0.63) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL19418365 | 0.79 | F13A1 (0.48) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL10150033 | 0.79 | F13A1 (0.59) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL19418371 | 0.78 | F13A1 (0.45) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL19418311 | 0.78 | F13A1 (0.45) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL20840810 | 0.77 | F13A1 (0.40) | F13A1TGM2MKNK2HSP90AB1GEMIN4 | |
| SCHEMBL20840824 | 0.76 | F13A1 (0.37) | F13A1TGM2MKNK2HSP90AB1GEMIN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239856-B2 | Synthesis of resorcylic acid lactones useful as therapeutic agents | UNIVERSITY DE STRASBOURG (FR) | 2019-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239856-B2 | Synthesis of resorcylic acid lactones useful as therapeutic agents | HSP90AA1, HSP90AB1, HSP90AB2P | F13A1 3830/4885TGM2 2199/4885MKNK2 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.