Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 18/20 | 0.51 |
| ▸ | ESRRB | O95718 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 8/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD5 | P21918 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24505518 | 0.86 | ESRRG (0.51) | ESRRGESRRBKCNH2ESR1HTR1A | |
| SCHEMBL20842009 | 0.84 | ESRRG (0.73) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL24354543 | 0.78 | ESRRG (0.70) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL24505410 | 0.75 | ESRRG (0.56) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL20978458 | 0.72 | ESRRG (0.75) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL20978521 | 0.71 | ESRRG (0.58) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL20842131 | 0.70 | ESRRG (0.73) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL24505447 | 0.70 | ESRRG (0.73) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL24354544 | 0.70 | ESRRG (0.64) | ESRRGESRRBKCNH2ESR1 | |
| SCHEMBL24505508 | 0.69 | ESRRG (0.77) | ESRRGESRRBKCNH2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480186-B1 | NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | NOVMETAPHARMA CO LTD (KR) | 2022-06-15 | — | — | EP | disclosed |
| EP-3459936-B1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-04-27 | — | — | EP | disclosed |
| EP-3459936-A1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | Kemimedi Co. Ltd (KR) | 2019-03-27 | — | — | EP | disclosed |