Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613990 | 0.86 | DHODH (0.69) | DHODHGAAGSTO1MGAMSI | |
| SCHEMBL20956565 | 0.84 | DHODH (1.00) | DHODHGSTO1MAPTKDM4EPOLB | |
| SCHEMBL29911563 | 0.84 | DHODH (1.00) | DHODHGSTO1MAPTKDM4EPOLB | |
| SCHEMBL19631365 | 0.84 | DHODH (1.00) | DHODHGSTO1MAPTKDM4EPOLB | |
| SCHEMBL25613895 | 0.83 | DHODH (0.66) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL16742081 | 0.83 | DHODH (0.72) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL16742080 | 0.83 | DHODH (0.72) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631392 | 0.81 | DHODH (0.78) | DHODHGSTO1MAPTKDM4EPOLB | |
| SCHEMBL20836121 | 0.80 | DHODH (1.00) | DHODHGAAGSTO1MGAMSI | |
| SCHEMBL19631464 | 0.80 | DHODH (1.00) | DHODHGAAGSTO1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459937-B1 | THIAZOLE DERIVATIVE AND APPLICATIONS | UNIV EAST CHINA SCIENCE & TECH (CN) | 2021-12-29 | — | — | EP | disclosed |
| EP-3459937-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS | East China University of Science and Technology (CN) | 2019-03-27 | — | — | EP | disclosed |