Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.59 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456764 | 0.93 | NR1H4 (0.58) | NR1H4HSD17B13PPARD | |
| SCHEMBL16456746 | 0.90 | NR1H4 (0.58) | NR1H4HSD17B13PPARD | |
| SCHEMBL16456777 | 0.89 | NR1H4 (0.58) | NR1H4HSD17B13 | |
| SCHEMBL2084564 | 0.87 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL16456837 | 0.85 | NR1H4 (0.59) | NR1H4HSD17B13PPARD | |
| SCHEMBL16456797 | 0.85 | NR1H4 (0.60) | NR1H4HSD17B13PPARD | |
| SCHEMBL16456791 | 0.85 | NR1H4 (0.60) | NR1H4HSD17B13PPARD | |
| SCHEMBL16456802 | 0.84 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL16456868 | 0.83 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL16456821 | 0.82 | NR1H4 (0.65) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984360-B1 | Compounds and methods for modulating FX-receptors | LILLY CO ELI (US) | 2014-01-15 | — | — | EP | claimed |
| US-7863302-B2 | Compounds and methods for modulating FX-receptors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | claimed |
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2008-12-11 | — | — | US | claimed |
| EP-1984360-B1 | Compounds and methods for modulating FX-receptors | LILLY CO ELI (US) | 2014-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306125-A1 | Compounds and Methods for Modulating Fx-Receptors | F2R, TBXA2R, PTAFR | NR1H4 65/4885HSD17B13 983/4885PPARD 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.