Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Labuxtinib SCHEMBL24508232 | 1.00 | KIT (1.00) | KIT | |
| Labuxtinib SCHEMBL14738734 | 1.00 | KIT (1.00) | KIT | |
| Labuxtinib SCHEMBL14738252 | 1.00 | KIT (1.00) | KIT | |
| Labuxtinib SCHEMBL14751407 | 1.00 | KIT (1.00) | KIT | |
| Labuxtinib SCHEMBL14739429 | 1.00 | KIT (1.00) | KIT | |
| Labuxtinib SCHEMBL29562904 | 0.99 | KIT (0.98) | KIT | |
| Labuxtinib SCHEMBL29441810 | 0.95 | KIT (0.91) | KIT | |
| SCHEMBL14738439 | 0.92 | KIT (1.00) | KIT | |
| SCHEMBL27336503 | 0.91 | KIT (0.84) | KIT | |
| SCHEMBL14738475 | 0.91 | KIT (1.00) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751102-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-03-27 | — | — | EP | disclosed |