⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16613140 | 0.73 | — | — | |
| SCHEMBL308800 | 0.73 | — | — | |
| SCHEMBL1270192 | 0.73 | — | — | |
| SCHEMBL7833709 | 0.73 | — | — | |
| SCHEMBL10771642 | 0.73 | — | — | |
| SCHEMBL23922953 | 0.69 | — | — | |
| SCHEMBL16174998 | 0.69 | — | — | |
| SCHEMBL14677559 | 0.69 | — | — | |
| SCHEMBL1246820 | 0.67 | — | — | |
| SCHEMBL27023 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 939 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113286792-B | N-chromen-4-one containing derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-12-05 | — | — | CN | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| US-20220169639-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2022-06-02 | — | — | US | claimed |
| EP-3894402-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2021-10-20 | — | — | EP | claimed |
| CN-113286792-A | N-containing chromen-4-one derivatives for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-20 | — | — | CN | claimed |
| WO-2020120528-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-18 | — | — | WO | claimed |
| EP-2450374-B9 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-11-23 | — | — | EP | claimed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| US-20160311934-A1 | HYDROXYALKYL STARCH DERIVATIVES AS REACTANTS FOR COUPLING TO THIOL GROUPS | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2016-10-27 | — | — | US | claimed |
| US-9260500-B2 | Peptide and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-02-16 | — | — | US | claimed |
| US-4801580-A | Peptide, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1989-01-31 | — | — | US | claimed |
| US-4797414-A | Naphthothiophene derivatives and their use as respiratory enhancing agents | ZYMA SA (CH) | 1989-01-10 | — | — | US | claimed |
| US-4749691-A | Peptide, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-07 | — | — | US | claimed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | claimed |
| US-4725582-A | IMMUNE RESPONSE ENHANCERS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1988-02-16 | — | — | US | claimed |
| EP-0250013-A1 | Technetium chelates to be used for determining the renal function | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1987-12-23 | — | — | EP | claimed |
| EP-0025842-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-03 | — | — | EP | claimed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | claimed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | claimed |
| US-4180395-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-12-25 | — | — | US | claimed |