Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847566 | 0.87 | HDAC6 (0.52) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847550 | 0.85 | HDAC6 (0.68) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847638 | 0.83 | HDAC6 (0.62) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847560 | 0.83 | HDAC6 (0.54) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20839227 | 0.82 | HDAC6 (0.69) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847603 | 0.82 | HDAC6 (0.65) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847554 | 0.82 | HDAC6 (0.69) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847484 | 0.82 | HDAC6 (0.64) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847557 | 0.82 | HDAC6 (0.65) | HDAC6HDAC8HDAC11L3MBTL1HDAC3 | |
| SCHEMBL20847601 | 0.81 | HDAC6 (0.63) | HDAC6HDAC8HDAC11HDAC3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2020-09-03 | — | — | US | disclosed |
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | MKI67, PKD1, ETV6 | HDAC6 499/4885HDAC8 1916/4885HDAC11 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.