Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.51 |
| ▸ | TEC | P42680 | 3/20 | 0.41 |
| ▸ | TXK | P42681 | 3/20 | 0.41 |
| ▸ | BMX | P51813 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468774 | 0.99 | BTK (0.50) | BTKTECTXKBMXKDM1A | |
| SCHEMBL20847983 | 0.92 | BTK (0.48) | BTKTECTXKBMXKDM1A | |
| SCHEMBL22887250 | 0.91 | BTK (0.47) | BTKTECTXKBMXKDM1A | |
| SCHEMBL19002013 | 0.90 | BTK (0.52) | BTKTECTXKBMXKDM1A | |
| SCHEMBL20468627 | 0.89 | BTK (0.51) | BTKTECTXKBMXKDM1A | |
| SCHEMBL19836085 | 0.89 | BTK (0.62) | BTKTECTXKBMX | |
| SCHEMBL22887287 | 0.89 | BTK (0.51) | BTKTECTXKBMXKDM1A | |
| SCHEMBL18996894 | 0.88 | BTK (0.66) | BTKTECTXKBMX | |
| SCHEMBL22887242 | 0.88 | BTK (0.50) | BTKTECTXKBMXKDM1A | |
| SCHEMBL19836228 | 0.81 | BTK (0.60) | BTKTECTXKBMXKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190092759-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092759-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LCK | BTK 1/4885TEC 7/4885TXK 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.