Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037448 | 1.00 | NPC1 (0.36) | NPC1RAB9AKMT2AMAPTPSMD14 | |
| SCHEMBL15037472 | 1.00 | NPC1 (0.36) | NPC1RAB9AKMT2AMAPTPSMD14 | |
| SCHEMBL15018684 | 0.96 | CYP1A2 (0.32) | NPC1RAB9AKMT2AMAPTPSMD14 | |
| SCHEMBL15018604 | 0.96 | CYP1A2 (0.32) | NPC1RAB9AKMT2AMAPTPSMD14 | |
| SCHEMBL20853519 | 0.94 | CYP1A2 (0.30) | NPC1RAB9AMAPTGAACYP1A2 | |
| SCHEMBL16369064 | 0.94 | CYP1A2 (0.30) | NPC1RAB9AMAPTGAACYP1A2 | |
| SCHEMBL20853538 | 0.93 | CHUK (0.32) | NPC1RAB9AMAPTGAACYP1A2 | |
| SCHEMBL15037538 | 0.93 | CHUK (0.32) | NPC1RAB9AMAPTGAACYP1A2 | |
| SCHEMBL15018630 | 0.92 | CYP2C9 (0.32) | NPC1RAB9AKMT2AMAPTPSMD14 | |
| SCHEMBL16369058 | 0.92 | CYP2C9 (0.32) | NPC1RAB9AKMT2AMAPTPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791250-B1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | OREAL (FR) | 2019-04-03 | — | — | EP | claimed |