⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607434 | 0.66 | — | — | |
| SCHEMBL3361218 | 0.65 | — | — | |
| SCHEMBL448999 | 0.64 | — | — | |
| SCHEMBL7296782 | 0.62 | — | — | |
| SCHEMBL7369663 | 0.62 | — | — | |
| SCHEMBL1325172 | 0.62 | — | — | |
| SCHEMBL2042953 | 0.62 | — | — | |
| SCHEMBL29035859 | 0.61 | — | — | |
| SCHEMBL28166931 | 0.61 | — | — | |
| SCHEMBL28272113 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240417401-A1 | HETEROBICYCLIC-METHYLPURINE PYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING DISEASES AND CONDITIONS | K36 THERAPEUTICS, INC. | 2024-12-19 | — | — | US | disclosed |
| CN-116801870-A | Solid pharmaceutical composition and method for producing the same | 加尔维塔股份公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114702454-A | Preparation method of 5-alkyl-11-aryl-5H-dibenzo [ b, e ] [1,4] diazepine derivative | 江西师范大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-110352190-A | Sulphur oxygroup alkyl Organic nitro and related compound and pharmaceutical composition for medical application | 埃皮辛特瑞柯斯公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-109563516-A | GPR156 variants and uses thereof | 雷杰纳荣制药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-103827440-A | Apparatus and methods utilizing nonexplosive energetic materials for downhole applications | BAKER HUGHES INC | 2014-05-28 | — | — | CN | disclosed |
| US-8163756-B2 | For example,1-(3-t-butyl-1- (1,2,3,4-tetrahydro- isoquinolin-6-yl)-1H- pyrazol-5-yl)-3-(3- cyanophenyl)urea; for treatment of mammalian cancers and inflammatory diseases including rheumatoid arthritis, retinopathies | DECIPHERA PHARMACEUTICALS, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20080113967-A1 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2008-05-15 | — | — | US | disclosed |
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| CN-1980923-A | Polycyclic pyridines as potassium ion channel modulators | ICAGEN INC (US) | 2007-06-13 | — | — | CN | disclosed |
| US-20070078121-A1 | Enzyme modulators and treatments | DECIPHERA PHARMACEUTICALS, LLC | 2007-04-05 | — | — | US | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |