Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184292 | 0.88 | TSHR (0.37) | TSHR | |
| SCHEMBL15547358 | 0.84 | FUCA1 (0.31) | — | |
| SCHEMBL19861006 | 0.80 | MAPT (0.33) | — | |
| SCHEMBL4685744 | 0.77 | FUCA1 (0.34) | — | |
| SCHEMBL19123244 | 0.74 | FUCA1 (0.30) | — | |
| SCHEMBL19936492 | 0.71 | GBA1 (0.34) | — | |
| SCHEMBL24449726 | 0.70 | — | — | |
| SCHEMBL21078053 | 0.70 | — | — | |
| SCHEMBL12616207 | 0.70 | — | — | |
| SCHEMBL12616434 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461827-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Cadent Therapeutics, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |