Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030123 | 0.93 | ABCB1 (0.57) | ABCB1 | |
| SCHEMBL20858957 | 0.92 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL20858997 | 0.91 | ABCB1 (0.57) | ABCB1MAPT | |
| SCHEMBL20858993 | 0.91 | ABCB1 (0.60) | ABCB1 | |
| SCHEMBL7026331 | 0.90 | ABCB1 (0.49) | ABCB1MAPTNPSR1 | |
| SCHEMBL20858964 | 0.89 | ABCB1 (0.49) | ABCB1MAPTNPSR1 | |
| SCHEMBL20858974 | 0.87 | ABCB1 (0.57) | ABCB1MAPT | |
| SCHEMBL20858975 | 0.86 | ABCB1 (0.47) | ABCB1MAPTNPSR1 | |
| SCHEMBL744982 | 0.84 | ABCB1 (0.62) | ABCB1MAPT | |
| SCHEMBL746215 | 0.84 | ABCB1 (0.67) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429292-B1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | GEORGIA STATE UNIV RESEARCH FOUNDATION (US) | 2019-04-03 | — | — | EP | disclosed |