Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613674 | 1.00 | DPP4 (0.50) | DPP4DPP8ELANEOPRM1OPRD1 | |
| SCHEMBL16703858 | 1.00 | DPP4 (0.50) | DPP4DPP8ELANEOPRM1OPRD1 | |
| SCHEMBL19603004 | 1.00 | DPP4 (0.50) | DPP4DPP8ELANEOPRM1OPRD1 | |
| SCHEMBL16703281 | 1.00 | DPP4 (0.50) | DPP4DPP8ELANEOPRM1OPRD1 | |
| SCHEMBL16703282 | 1.00 | DPP4 (0.50) | DPP4DPP8ELANEOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL31444858 | 0.99 | DPP4 (0.49) | DPP4DPP8ELANEOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL29613658 | 0.99 | DPP4 (0.49) | DPP4DPP8ELANEOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL18094987 | 0.99 | DPP4 (0.49) | DPP4DPP8ELANEOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL16703178 | 0.99 | DPP4 (0.49) | DPP4DPP8ELANEOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL16703176 | 0.99 | DPP4 (0.49) | DPP4DPP8ELANEOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066091-B1 | NMDA ANTAGONIST PRODRUGS | ASTRAZENECA AB (SE) | 2019-04-03 | — | — | EP | disclosed |