Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17670971 | 1.00 | DRD1 (0.57) | DRD1DRD4XIAPPOLBCYP3A4 | |
| SCHEMBL17670977 | 0.93 | DRD1 (0.50) | DRD1DRD4XIAPPOLBCYP3A4 | |
| SCHEMBL20862347 | 0.93 | DRD1 (0.50) | DRD1DRD4XIAPPOLBCYP3A4 | |
| SCHEMBL17674575 | 0.87 | DRD1 (0.67) | DRD1XIAPPOLBTAS1R3TAS1R1 | |
| SCHEMBL17674681 | 0.87 | DRD1 (0.67) | DRD1XIAPPOLBTAS1R3TAS1R1 | |
| SCHEMBL17674616 | 0.87 | DRD1 (0.67) | DRD1XIAPPOLBTAS1R3TAS1R1 | |
| SCHEMBL17674718 | 0.81 | DRD1 (0.60) | DRD1DRD4XIAPPOLBTAS1R3 | |
| SCHEMBL17674582 | 0.81 | DRD1 (0.56) | DRD1XIAPPOLBMAPT | |
| SCHEMBL17674648 | 0.81 | DRD1 (0.56) | DRD1XIAPPOLBMAPT | |
| SCHEMBL17670972 | 0.77 | DRD1 (0.77) | DRD1DRD4CYP3A4HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204374-B1 | ISOINDOLINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2019-04-03 | — | — | EP | disclosed |