⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL29086472 | 0.95 | HSP90AA1 (0.44) | — | |
| SCHEMBL27986259 | 0.80 | — | — | |
| SCHEMBL4630887 | 0.79 | GSK3A (0.53) | — | |
| Hydrochloric Acid SCHEMBL7857018 | 0.77 | GSK3A (0.51) | — | |
| SCHEMBL30488472 | 0.75 | — | — | |
| SCHEMBL7854417 | 0.75 | — | — | |
| SCHEMBL29608372 | 0.75 | — | — | |
| SCHEMBL26698946 | 0.75 | — | — | |
| SCHEMBL311748 | 0.75 | — | — | |
| SCHEMBL27708097 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652204-A | A kind of epoxides grafting hydrazine reduction prepares and the method for dispersed graphite alkene | 山东理工大学 | 2018-02-02 | — | — | CN | claimed |
| CN-103435555-B | Preparation method of 4-chloro-5-methylpyrimidine | WYLTON JINGLIN ELECTRONIC MATERIAL CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-103435555-A | Preparation method of 4-chloro-5-methylpyrimidine | WYLTON JINGLIN ELECTRONIC MATERIAL CO LTD | 2013-12-11 | — | — | CN | claimed |
| EP-4707276-A2 | MALT1 MODULATORS AND USES THEREOF | Rarefied Biosciences, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20260062391-A1 | HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4499611-B1 | MALT1 MODULATORS AND USES THEREOF | RAREFIED BIOSCIENCES INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20250326738-A1 | MALT1 Modulators and Uses Thereof | RAREFIED BIOSCIENCES, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| US-12291508-B2 | Hydrazide containing nuclear transport modulators and uses thereof | Karyopharm Therapeutics Inc. (US) | 2025-05-06 | — | — | US | disclosed |
| EP-4499611-A1 | MALT1 MODULATORS AND USES THEREOF | Rarefied Biosciences, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119032083-A | MALT1 modulators and uses thereof | 稀有生物科学股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4456900-A1 | RESPIRATORY STIMULANT PARENTERAL FORMULATIONS | Enalare Therapeutics Inc. (US) | 2024-11-06 | — | — | EP | disclosed |
| US-4479955-A | ANTICONVULSANTS, ANTIDEPRESSANTS, ANTIEPILEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0115469-A1 | Pyrazolo(3,4-d)pyridin-3-ones condensed with a heterocycle | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | disclosed |
| EP-0032131-B1 | 5-HALO-PYRIMIDIN-2-ONES, THE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NYEGAARD & CO. A/S (NO) | 1983-09-21 | — | — | EP | disclosed |
| US-4399140-A | CYTOTOXIC | NYEGAARD & CO. A/S (NO) | 1983-08-16 | — | — | US | disclosed |
| EP-0000383-B1 | PYRIMIDO (4,5-C) PYRIDAZINES, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESS FOR THEIR PREPARATION | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-10-13 | — | — | EP | disclosed |
| US-4328223-A | 2-Amino-3a,4,5,6-tetrahydro-perimidine derivatives and their medicinal use in combatting circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |
| EP-0032131-A1 | 5-Halo-pyrimidin-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them | NYEGAARD & CO. A/S (NO) | 1981-07-15 | — | — | EP | disclosed |
| US-4269980-A | TRANQUILIZERS; ANTICONVULSANTS | AMERICAN CYANAMID COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| EP-0004904-A1 | 2-Amino-3a,4,5,6-tetrahydroperimidine derivatives, medicaments containing them and process for their preparation | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |