Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 10/20 | 0.80 |
| ▸ | FEN1 | P39748 | 14/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20864081 | 0.89 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864257 | 0.89 | ERCC5 (0.79) | ERCC5FEN1 | |
| SCHEMBL25053679 | 0.88 | FEN1 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864245 | 0.86 | FEN1 (1.00) | ERCC5FEN1 | |
| SCHEMBL25053686 | 0.84 | ERCC5 (0.75) | ERCC5FEN1 | |
| SCHEMBL20864222 | 0.84 | FEN1 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864151 | 0.84 | FEN1 (1.00) | ERCC5FEN1 | |
| SCHEMBL20856801 | 0.83 | FEN1 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864228 | 0.83 | ERCC5 (1.00) | ERCC5FEN1 | |
| SCHEMBL20864409 | 0.82 | FEN1 (1.00) | ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067442-A1 | DIHYDROTHIENO[3,2-b]PYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2019-04-04 | — | — | WO | disclosed |