Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMTK3 | Q96Q04 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.77 |
| ▸ | NTRK1 | P04629 | 8/20 | 0.72 |
| ▸ | PRKCQ | Q04759 | 7/20 | 0.72 |
| ▸ | KDR | P35968 | 7/20 | 0.72 |
| ▸ | MAP3K11 | Q16584 | 6/20 | 0.72 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.72 |
| ▸ | PRKCA | P17252 | 5/20 | 0.72 |
| ▸ | PRKCH | P24723 | 5/20 | 0.72 |
| ▸ | PRKCI | P41743 | 5/20 | 0.72 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.72 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.72 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.72 |
| ▸ | MAP3K9 | P80192 | 5/20 | 0.72 |
| ▸ | PRKCG | P05129 | 4/20 | 0.72 |
| ▸ | PRKCB | P05771 | 4/20 | 0.72 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.72 |
| ▸ | MYLK | Q15746 | 4/20 | 0.72 |
| ▸ | MAP3K10 | Q02779 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865117 | 0.92 | PRKCQ (0.65) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865122 | 0.91 | PRKCQ (0.71) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865256 | 0.91 | PRKCQ (0.71) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865167 | 0.91 | LMTK3 (0.81) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865173 | 0.90 | LMTK3 (0.85) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865257 | 0.90 | PRKCQ (0.70) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865113 | 0.90 | LMTK3 (0.69) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865111 | 0.89 | LMTK3 (0.66) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865155 | 0.89 | LMTK3 (0.79) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865255 | 0.89 | PRKCQ (0.73) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067396-A1 | ZAP-70 KINASE INHIBITOR COMPOSITIONS, METHODS AND USES THEREOF | SNAP BIO, INC. (US) | 2019-04-04 | — | — | WO | disclosed |