Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865335 | 0.88 | EGFR (0.74) | EGFR | |
| SCHEMBL26750372 | 0.87 | EGFR (0.70) | EGFR | |
| SCHEMBL26750527 | 0.87 | EGFR (0.70) | EGFR | |
| SCHEMBL20865245 | 0.87 | EGFR (0.72) | EGFR | |
| SCHEMBL29394159 | 0.87 | EGFR (0.72) | EGFR | |
| SCHEMBL20865222 | 0.87 | EGFR (0.72) | EGFR | |
| SCHEMBL20856929 | 0.87 | EGFR (0.72) | EGFR | |
| SCHEMBL26750422 | 0.87 | EGFR (0.68) | EGFR | |
| SCHEMBL24328870 | 0.85 | EGFR (0.70) | EGFR | |
| SCHEMBL24328613 | 0.85 | EGFR (0.70) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081447-A1 | EGFR INHIBITORS FOR TREATING LUNG CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2019067543-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-04 | — | — | WO | disclosed |