Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248850 | 0.82 | CXCR2 (0.72) | CXCR2CXCR1 | |
| SCHEMBL14319675 | 0.70 | CXCR2 (0.36) | CXCR2CXCR1 | |
| SCHEMBL247336 | 0.69 | CXCR2 (0.74) | CXCR2CXCR1 | |
| SCHEMBL20865524 | 0.67 | CXCR1 (0.81) | CXCR2CXCR1 | |
| SCHEMBL20760855 | 0.66 | GAA (0.64) | CXCR2CXCR1 | |
| SCHEMBL18870051 | 0.65 | CXCR2 (0.66) | CXCR2CXCR1 | |
| SCHEMBL12087245 | 0.65 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL22388654 | 0.65 | CXCR1 (1.00) | CXCR2CXCR1 | |
| SCHEMBL14100317 | 0.65 | CXCR1 (0.59) | CXCR2CXCR1 | |
| SCHEMBL12086761 | 0.65 | CXCR1 (1.00) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067332-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER WITH A COMBINATION OF PROGRAMMED DEATH RECEPTOR (PD-1) ANTIBODIES AND A CXCR2 ANTAGONIST | MERCK SHARP & DOHME CORP. (US) | 2019-04-04 | — | — | WO | disclosed |