SCHEMBL20866204

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Erlotinib SCHEMBL2037601	0.95	EGFR (0.85)	EGFRERBB2GAKRIPK2BUB1
	Erlotinib SCHEMBL27974794	0.92	EGFR (0.82)	EGFRERBB2GAKRIPK2BUB1
	Erlotinib SCHEMBL2034496	0.91	EGFR (0.87)	EGFRERBB2GAKRIPK2BUB1
	Erlotinib SCHEMBL482681	0.90	EGFR (0.89)	EGFRERBB2GAKRIPK2BUB1
	Erlotinib SCHEMBL20721119	0.90	EGFR (0.89)	EGFRERBB2GAKRIPK2BUB1
	SCHEMBL30887945	0.89	EGFR (0.84)	EGFRERBB2GAKRIPK2BUB1
	SCHEMBL1507567	0.89	EGFR (0.84)	EGFRERBB2GAKRIPK2BUB1
	SCHEMBL1507474	0.89	EGFR (0.84)	EGFRERBB2GAKRIPK2BUB1
	Erlotinib SCHEMBL29120903	0.88	EGFR (0.96)	EGFRERBB2GAKRIPK2BUB1
	Erlotinib SCHEMBL3667407	0.88	EGFR (1.00)	EGFRERBB2GAKRIPK2BUB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.