Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.45 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | SCN2B | O60939 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20868418 | 0.92 | SCN9A (0.43) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL20868421 | 0.92 | SCN9A (0.43) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL20868290 | 0.92 | SCN9A (0.43) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL30512233 | 0.89 | SCN9A (0.44) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL30512211 | 0.89 | SCN9A (0.44) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL20868504 | 0.89 | SCN9A (0.44) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL20868181 | 0.89 | SCN9A (0.44) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL30512213 | 0.89 | SCN9A (0.44) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL20868008 | 0.89 | SCN9A (0.43) | SCN9ASCN7ASCN5ASCN2BSCN1A | |
| SCHEMBL20868182 | 0.89 | SCN9A (0.43) | SCN9ASCN7ASCN5ASCN2BSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019062848-A1 | N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2019-04-04 | — | — | WO | disclosed |