Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 9/20 | 0.51 |
| ▸ | SCN7A | Q01118 | 7/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 15/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20868549 | 0.92 | SCN9A (0.58) | SCN5ASCN7ASCN9ASCN1ASCN4A | |
| SCHEMBL20868018 | 0.90 | SCN7A (0.59) | SCN5ASCN7ASCN9ASCN1ASCN4A | |
| SCHEMBL20868075 | 0.88 | SCN9A (0.43) | SCN5ASCN7ASCN9A | |
| SCHEMBL29028584 | 0.87 | SCN9A (0.42) | SCN5ASCN7ASCN9A | |
| SCHEMBL20668636 | 0.84 | SCN7A (0.61) | SCN5ASCN7ASCN9ASCN1ASCN4A | |
| SCHEMBL20868057 | 0.83 | SCN5A (0.55) | SCN5ASCN7ASCN9ASCN1ASCN4A | |
| SCHEMBL20868153 | 0.82 | SCN5A (0.62) | SCN5ASCN7ASCN9ASCN1ASCN4A | |
| SCHEMBL20868267 | 0.82 | SCN9A (0.51) | SCN5ASCN7ASCN9ASCN1ASCN4A | |
| SCHEMBL20868269 | 0.80 | SCN9A (0.56) | SCN5ASCN7ASCN9A | |
| SCHEMBL20868012 | 0.80 | SCN9A (0.60) | SCN5ASCN7ASCN9ASCN1ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212830-B | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-111212830-A | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2020-05-29 | — | — | CN | disclosed |
| WO-2019062848-A1 | N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2019-04-04 | — | — | WO | disclosed |