Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101760 | 1.00 | EGFR (0.44) | EGFRKDM4AAAK1ALDH1A1CYP1A2 | |
| SCHEMBL19201249 | 0.89 | KDM4A (0.44) | KDM4AAAK1HDAC1NPC1RECQL | |
| SCHEMBL8011978 | 0.87 | AAK1 (0.47) | KDM4AAAK1NPC1RECQLRAB9A | |
| SCHEMBL31142972 | 0.87 | AAK1 (0.47) | KDM4AAAK1NPC1RECQLRAB9A | |
| SCHEMBL18719605 | 0.87 | KDM4A (0.45) | KDM4AAAK1ALDH1A1NPC1RECQL | |
| SCHEMBL4090969 | 0.86 | EGFR (0.45) | EGFRAAK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4471744 | 0.86 | KDM4A (0.44) | KDM4AAAK1NPC1RECQLRAB9A | |
| SCHEMBL30101829 | 0.86 | AAK1 (0.46) | KDM4AAAK1NPC1RECQLRAB9A | |
| SCHEMBL1476859 | 0.84 | AAK1 (0.47) | KDM4AAAK1NPC1RECQLRAB9A | |
| SCHEMBL2520675 | 0.84 | AAK1 (0.46) | KDM4AAAK1NPC1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |