⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3463426 | 0.97 | — | — | |
| SCHEMBL31042646 | 0.88 | — | — | |
| SCHEMBL11811204 | 0.61 | — | — | |
| SCHEMBL2223430 | 0.58 | — | — | |
| SCHEMBL352623 | 0.56 | — | — | |
| SCHEMBL2868390 | 0.56 | — | — | |
| SCHEMBL2049131 | 0.54 | — | — | |
| SCHEMBL69662 | 0.52 | — | — | |
| SCHEMBL11773655 | 0.52 | — | — | |
| SCHEMBL380648 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109745309-B | Mitsuma as antiviral agent | 香港浸会大学 | 2022-01-28 | — | — | CN | disclosed |
| US-10323012-B2 | Miliusanes as antiviral agents | HONG KONG BAPTIST UNIVERSITY (HK) | 2019-06-18 | — | — | US | disclosed |
| US-20180065946-A1 | Miliusanes As Antiviral Agents | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-03-08 | — | — | US | disclosed |
| US-20180065946-A1 | Miliusanes As Antiviral Agents | HONG KONG BAPTIST UNIVERSITY (HK) | 2018-03-08 | — | — | US | disclosed |
| US-9822071-B2 | Anticancer miliusane lactams | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-11-21 | — | — | US | disclosed |
| US-9822071-B2 | Anticancer miliusane lactams | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-11-21 | — | — | US | disclosed |
| US-9822071-B2 | Anticancer miliusane lactams | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-11-21 | — | — | US | disclosed |
| US-20170267635-A1 | Anticancer Miliusane Lactams | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-09-21 | — | — | US | disclosed |
| US-20170267635-A1 | Anticancer Miliusane Lactams | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-09-21 | — | — | US | disclosed |
| US-9695141-B2 | Anticancer miliusane derivatives | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-07-04 | — | — | US | disclosed |
| US-7754708-B2 | N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof | TARGACEPT, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20100093788-A1 | HETEROCYCLIC BENZIMIDAZOLES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-04-15 | — | — | US | disclosed |
| US-20080242689-A1 | Analgesics, central nervous system disorders, obesity, side effect reduction | BHATTI BALWINDER | 2008-10-02 | — | — | US | disclosed |
| US-20080161331-A1 | Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2008-07-03 | — | — | US | disclosed |
| US-7384929-B2 | N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof | TARGACEPT, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| EP-1866294-A1 | COMPOUNDS COMPRISING AN OXAZOLINE OR THIAZOLINE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB Pharma, S.A. (BE) | 2007-12-19 | — | — | EP | disclosed |
| EP-1802601-A1 | AZASPIROALKENE AND AZAPIROALKANE COMPOUNDS WITH NICOTINIC CHOLINERGIC RECEPTOR ACTIVITY | Targacept, Inc. (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006103057-A1 | COMPOUNDS COMPRISING AN OXAZOLINE OR THIAZOLINE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA, S.A. (BE) | 2006-10-05 | — | — | WO | disclosed |
| US-20060074067-A1 | N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof | BHATTI BALWINDER | 2006-04-06 | — | — | US | disclosed |
| WO-2006034089-A1 | AZASPIROALKENE AND AZASPIROALKANE COMPOUNDS WITH NICOTINIC CHOLINERGIC RECEPTOR ACTIVITY | TARGACEPT, INC. (US) | 2006-03-30 | — | — | WO | disclosed |