Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 0.90 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873043 | 1.00 | KCNJ1 (0.90) | KCNJ1KCNH2 | |
| SCHEMBL19457857 | 0.95 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL19457707 | 0.95 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| Tartaric Acid SCHEMBL30378057 | 0.91 | KCNJ1 (0.93) | KCNJ1KCNH2 | |
| SCHEMBL19457878 | 0.89 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL19457879 | 0.89 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL19457703 | 0.87 | KCNJ1 (0.85) | KCNJ1KCNH2 | |
| SCHEMBL19457859 | 0.87 | KCNJ1 (0.85) | KCNJ1KCNH2 | |
| SCHEMBL15757970 | 0.87 | KCNJ1 (0.85) | KCNJ1KCNH2 | |
| SCHEMBL15757966 | 0.87 | KCNJ1 (0.85) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466945-A1 | PHARMACEUTICALLY ACCEPTABLE SALT AS RENAL OUTER MEDULLARY POTASSIUM CHANNEL INHIBITOR | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2019-04-10 | — | — | EP | disclosed |