Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.63 |
| ▸ | EGFR | P00533 | 8/20 | 0.55 |
| ▸ | LCK | P06239 | 2/20 | 0.54 |
| ▸ | ITK | Q08881 | 2/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065717 | 1.00 | BTK (0.63) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL17065778 | 1.00 | BTK (0.63) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL20873643 | 0.93 | BTK (0.54) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL16594568 | 0.91 | EGFR (0.65) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL16594566 | 0.91 | EGFR (0.65) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL16594569 | 0.91 | EGFR (0.65) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL16594562 | 0.91 | EGFR (0.65) | BTKEGFRLCKITKFGFR2 | |
| SCHEMBL17065706 | 0.91 | BTK (0.63) | BTKEGFR | |
| SCHEMBL17065710 | 0.91 | BTK (0.63) | BTKEGFR | |
| SCHEMBL17065673 | 0.91 | BTK (0.77) | BTKEGFRLCKITKFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102579-B1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LTD (IN) | 2019-04-10 | — | — | EP | claimed |