SCHEMBL208780

SCHEMBL208780

C1=COC2NCSC2=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29102107 0.65
SCHEMBL22408836 0.54
SCHEMBL4559978 0.54
SCHEMBL3576495 0.53
SCHEMBL7162800 0.51
SCHEMBL1315681 0.48
SCHEMBL19134041 0.48
SCHEMBL3076735 0.47
SCHEMBL18721816 0.47
SCHEMBL8389794 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256465-B 2, 4-diaminopyrimidine containing dihydropyranothiazole and application thereof 南方医科大学 2021-08-13 CN claimed
CN-107759619-B Dihydropyrano-thiazole ring compound and preparation method and application thereof 中国医药集团总公司四川抗菌素工业研究所 2020-03-20 CN claimed
EP-2602242-A1 PROCESS FOR PREPARING COMPOUND BY NOVEL SANDMEYER-LIKE REACTION USING NITROXIDE RADICAL COMPOUND AS REACTION CATALYST DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-12 EP claimed
US-20130144061-A1 PROCESS FOR PREPARING A COMPOUND BY A NOVEL SANDMEYER-LIKE REACTION USING A NITROXIDE RADICAL COMPOUND AS A REACTION CATALYST DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-06-06 US claimed
CN-110256465-B 2, 4-diaminopyrimidine containing dihydropyranothiazole and application thereof 南方医科大学 2021-08-13 CN disclosed
CN-110256465-B 2, 4-diaminopyrimidine containing dihydropyranothiazole and application thereof 南方医科大学 2021-08-13 CN disclosed
CN-110256465-B 2, 4-diaminopyrimidine containing dihydropyranothiazole and application thereof 南方医科大学 2021-08-13 CN disclosed
CN-107759619-B Dihydropyrano-thiazole ring compound and preparation method and application thereof 中国医药集团总公司四川抗菌素工业研究所 2020-03-20 CN disclosed
CN-107759619-B Dihydropyrano-thiazole ring compound and preparation method and application thereof 中国医药集团总公司四川抗菌素工业研究所 2020-03-20 CN disclosed
CN-107759619-B Dihydropyrano-thiazole ring compound and preparation method and application thereof 中国医药集团总公司四川抗菌素工业研究所 2020-03-20 CN disclosed
CN-107739386-B Crystal form of dihydropyranothiazole compound and preparation method thereof 中国医药集团总公司四川抗菌素工业研究所 2020-03-20 CN disclosed
CN-107739386-B Crystal form of dihydropyranothiazole compound and preparation method thereof 中国医药集团总公司四川抗菌素工业研究所 2020-03-20 CN disclosed
EP-1577302-A1 NOVEL ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
US-20050119486-A1 Diamine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2005-06-02 US disclosed
US-20050020645-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-01-27 US disclosed
US-20040122063-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-24 US disclosed
EP-1415992-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-05-06 EP disclosed
EP-1405852-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-07 EP disclosed
EP-1270557-A1 ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-01-02 EP disclosed