Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 16/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406375 | 0.88 | XPO1 (0.60) | XPO1 | |
| SCHEMBL20880362 | 0.86 | XPO1 (0.54) | XPO1SORT1 | |
| SCHEMBL1592486 | 0.81 | XPO1 (0.48) | XPO1HSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL4996443 | 0.76 | XPO1 (0.53) | XPO1ALDH1A1 | |
| SCHEMBL23872317 | 0.75 | XPO1 (0.51) | XPO1SORT1ALDH1A1 | |
| SCHEMBL1593014 | 0.74 | XPO1 (0.46) | XPO1 | |
| SCHEMBL23872050 | 0.74 | XPO1 (0.43) | XPO1 | |
| SCHEMBL4992534 | 0.73 | XPO1 (0.72) | XPO1 | |
| SCHEMBL1592490 | 0.73 | XPO1 (0.52) | XPO1 | |
| SCHEMBL24465034 | 0.72 | XPO1 (0.53) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567035-A1 | N-SUBSTITUTED 2,5-DIOXO-AZOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Canbas Co. Ltd. (JP) | 2019-11-13 | — | — | EP | disclosed |
| EP-3088397-B1 | COMPOUNDS THAT ABROGATE THE CELL CYCLE G2 CHECKPOINT FOR USE IN THE TREATMENT OF CANCER | CANBAS CO LTD (JP) | 2019-04-10 | — | — | EP | disclosed |