Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14932215 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16162763 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16169905 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16169903 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16169902 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16169906 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16169907 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16163060 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL14932228 | 1.00 | KCNJ1 (1.00) | KCNJ1 | |
| SCHEMBL16162751 | 1.00 | KCNJ1 (1.00) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773199-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2019-04-10 | — | — | EP | disclosed |