Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20885274 | 1.00 | SYK (0.54) | SYKPPARACTSSATMCTSL | |
| SCHEMBL22579840 | 1.00 | SYK (0.54) | SYKPPARACTSSATMCTSL | |
| SCHEMBL20854198 | 1.00 | SYK (0.54) | SYKPPARACTSSATMCTSL | |
| SCHEMBL28432305 | 0.90 | SYK (0.57) | SYKCTSSATMCTSLCTSK | |
| SCHEMBL30198452 | 0.90 | SYK (0.57) | SYKCTSSATMCTSLCTSK | |
| SCHEMBL20869906 | 0.90 | SYK (0.57) | SYKCTSSATMCTSLCTSK | |
| SCHEMBL20885241 | 0.90 | SYK (0.57) | SYKCTSSATMCTSLCTSK | |
| SCHEMBL6388701 | 0.90 | KLK5 (0.57) | SYKPPARACTSSATMCTSL | |
| SCHEMBL12873000 | 0.90 | KLK5 (0.57) | SYKPPARACTSSATMCTSL | |
| SCHEMBL12214464 | 0.90 | KLK5 (0.57) | SYKPPARACTSSATMCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019070595-A1 | AZTREONAM DERIVATIVES AND USES THEREOF | ARIXA PHARMACEUTICALS, INC. (US) | 2019-04-11 | — | — | WO | disclosed |