Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869566 | 1.00 | MAPT (0.48) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL8180829 | 0.92 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL20869521 | 0.92 | MAPT (0.45) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL20869522 | 0.92 | MAPT (0.45) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL20869619 | 0.90 | NR1I2 (0.41) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL8176515 | 0.90 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL8176517 | 0.90 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL20869564 | 0.89 | MAPT (0.60) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL20886828 | 0.89 | MAPT (0.60) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL17489333 | 0.89 | MAPT (0.44) | MAPTALDH1A1USP2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019070973-A1 | CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2019-04-11 | — | — | WO | disclosed |